Today, various studies point to the potential of psilocybin to assist with treatment-resistant depression, end-of-life distress, obsessive-compulsive disorder, eating disorders, and substance-use disorders, including alcohol and tobacco addiction. This has led to growing interest in the use of psilocybin mushrooms—not only for high-dose experiences, but also as a tool for microdosing. Psilocybin Mushroom Store Detroit. In summary, we’re seeing both mental and physical benefits from the intentional use of psilocybin mushrooms, microdose and macrodose.